CDS
| Accession Number | TCMCG077C14687 |
| gbkey | CDS |
| Protein Id | KAF5739943.1 |
| Location | complement(join(99013..99183,99704..99758,99854..99900,99999..100055,100181..100292,100946..101027,101148..101232,101306..101425,102043..102093,102220..102285,102426..102473,102561..102609,102750..102803,102907..102966,103131..103189,103267..103344)) |
| Organism | Tripterygium wilfordii |
| locus_tag | HS088_TW11G00005 |
Protein
| Length | 397aa |
| Molecule type | protein |
| Topology | linear |
| Data_file_division | PLN |
| dblink | BioProject:PRJNA542587, BioSample:SAMN11634134 |
| db_source | JAAARO010000011.1 |
| Definition | flap endonuclease 1 isoform X1 [Tripterygium wilfordii] |
| Locus_tag | HS088_TW11G00005 |
EGGNOG-MAPPER Annotation
| COG_category | L |
| Description | Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic apyrimidinic (AP) site-terminated flap. Acts as a genome stabilization factor that prevents flaps from equilibrating into structurs that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double- stranded DNA, and exhibits RNase H activity. Also involved in replication and repair of rDNA and in repairing mitochondrial DNA |
| KEGG_TC | - |
| KEGG_Module | - |
| KEGG_Reaction | - |
| KEGG_rclass | - |
| BRITE |
ko00000
[VIEW IN KEGG] ko00001 [VIEW IN KEGG] ko01000 [VIEW IN KEGG] ko03032 [VIEW IN KEGG] ko03400 [VIEW IN KEGG] ko04147 [VIEW IN KEGG] |
| KEGG_ko |
ko:K04799
[VIEW IN KEGG] |
| EC | - |
| KEGG_Pathway |
ko03030
[VIEW IN KEGG] ko03410 [VIEW IN KEGG] ko03450 [VIEW IN KEGG] map03030 [VIEW IN KEGG] map03410 [VIEW IN KEGG] map03450 [VIEW IN KEGG] |
| GOs | - |
Sequence
| CDS: ATGAAAGAACAGAAATTCGAAAGTTACTTCGGCAGGAAGATCGCTATCGATGCTAGCATGAGCATCTATCAGTTTCTCATTGTTGTAGGAAGAAGTGGGACTAAAATGCTCACAAATGAGGCTGGTGAAGTCACTAGTCATTTGCAGGGCATGTTTACTCGGACAATTAGACTTCTTGAAGCTGGAATGAAGCCTATCTATGTTTTTGATGGACAGCCTCCAGATTTGAAAAAACAAGAGCTGAAAAAACGTTATTCAAAGCGCGCAGATGCTACTGAGGAATTGGCAGCAGCTGTGGAGACTGGCAATAAAGAGGACATTGAGAAATTCAGTAAACGGACAGTGAAGGTGTCAAGGCAGCACAATGAAGATTGCAAAAGACTTCTGAAACTCATGGGTGTCCCTGTGATTGAGGCCCCTTCTGAAGCAGAGGCGCAATGTGTTGCACTTTGCAAATTGGGAAAGGTTTACGCTGTTGCTTCTGAAGACATGGATTCACTAACTTTTGGAGCTCCTAGGTTTCTCCGACATTTGATGGATCCTAGTTCTAGAAAAGTTTCAGTTATGGAATTTGAAGTTGCAAAGATTTTGGAGGAGCTGAATCTTACCATGGATCAATTCATCGACTTGTGCATTCTTTCAGGATGTGACTATTGTGGCAACATTAGAGGTATTGGGGGACAGACAGCTCTGAAACTGATACGTCAACATGGCTCTATTGAGACCGTACTAGAGAACATAAATAAAGAGATGTACCAAATACCAGCTGAGTGGCCATATCAAGAGGCTCAGAGACTTTTTAAAGAACCAGTTGTTAAAGATGAAGAGCAACTTGAGCTTAACTGGAGCGCTCCTGATGAAGAAGGGTTGATAACCTTCCTGGTAAATGAAAATGGGTTCAACAGTGACAGGGTAACAAAGGCAATAGAAAAAATTAAAGTGGCGAAGAACAAGTCATCCCAGGGACGATTAGAGTCATTTTTTAAGCCAGTTGCAAACACTTCTGTTCCTGTTAAACGGAAGGAAAGCAAATGTGTGCTCCGATCTCCAAAACCAGCCATGAAATTTAAGATGTTCTCTCCGCAAATCTCTAATTGTTTCATGTCCAAGGTCATTGGTGGCTTAGGGCTGCCTGCATATCTGGGCTCCAAGCATTCCATGCCATTAGCCAAAGGGGTCTGCTTCGGGGCATGA |
| Protein: MKEQKFESYFGRKIAIDASMSIYQFLIVVGRSGTKMLTNEAGEVTSHLQGMFTRTIRLLEAGMKPIYVFDGQPPDLKKQELKKRYSKRADATEELAAAVETGNKEDIEKFSKRTVKVSRQHNEDCKRLLKLMGVPVIEAPSEAEAQCVALCKLGKVYAVASEDMDSLTFGAPRFLRHLMDPSSRKVSVMEFEVAKILEELNLTMDQFIDLCILSGCDYCGNIRGIGGQTALKLIRQHGSIETVLENINKEMYQIPAEWPYQEAQRLFKEPVVKDEEQLELNWSAPDEEGLITFLVNENGFNSDRVTKAIEKIKVAKNKSSQGRLESFFKPVANTSVPVKRKESKCVLRSPKPAMKFKMFSPQISNCFMSKVIGGLGLPAYLGSKHSMPLAKGVCFGA |